HitFetcher™ Simultaneous Automated Hitpicking System

Black Dog is a supplier of lab automation solutions such as the HitFetcher™ Simultaneous Automated Hitpicking System. This compact, self-contained automated hitpicking system allows users to obtain assay plates comprised of the actual hits detected in a primary screen using the same compound source plates that provided the primary screen. The HitFetcher™ uses the output files produced by the plate reader as they become available, and automatically selects and transfers hits based on user-entered criteria. As each primary screen assay plate is finished, the HitFetcher™ immediately moves the hits to a secondary assay hit plate, and completely eliminates the possibility of receiving the wrong compounds in secondary screening plates.

The HitFetcher™ automate hitpicking system saves the need to return to the users compound storage library to run secondary or conformational screens of the hits in a primary screen. The hit-picked plates are prepared even while the primary screen is taking place, so the secondary or conformational screen can go forward without any delay. And, because the original source compound plates are being used, the secondary assay uses the same compound conditions of the primary screen. This eliminates any artifacts that may result from preparing secondary assay plates anew from the compound library.

The HitFetcher™ automated hitpicking system holds 30 original compound plates, 12 disposable tip boxes, and 30 secondary “hit” plates - and it’s easy to set up.

• Automatically cherry pick hits for same day re-testing with no additional effort
• Handles 96 well or 384 well microplates and tip boxes without physical setup changes
• Compatible with any HTS platform - or it can be used as a stand-alone pipettor for fluid transfer
• Finished “hit” plates can be removed at any time
• Easy-to-load and remove plate stacks
• Automatic barcode scanning and tracking
• Easy, flexible liquid-handler setup and method development

Contact Black Dog for more information and to request a quotation.